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Evidence for the validity and reliability of the ALS assessment questionnaire: the ALSAQ-40.

Author information

1
Health Services Research Unit, Division of Public Health & Primary Health Care, University of Oxford, Institute of Health Sciences, Headington, Oxford, OX3 7LF, UK.

Abstract

OBJECTIVES:

The purpose of the study was to assess the validity and reliability of a new disease specific measure of health-related quality of life for ALS/MND: the 40-item ALS Assessment Questionnaire (ALSAQ-40).

DESIGN:

We carried out a longitudinal postal survey. The two administrations of the questionnaire were separated by 3 months.

SAMPLE:

Subjects were patients diagnosed with ALS/MND and registered with the UK MND Association.

RESULTS:

Dimensions of the ALSAQ-40 were shown to have high levels of internal reliability. The ALSAQ-40 was found to be sensitive to changes in self reported overall health state.

CONCLUSION:

We concluded that the ALSAQ-40 has high levels of reliability and validity and can be used as an outcome measure in studies evaluating new treatment regimes and therapies.

PMID:
12365067
DOI:
10.1080/146608299300080022
[Indexed for MEDLINE]

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