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Nat Rev Cancer. 2002 Oct;2(10):727-39.

Clinical translation of angiogenesis inhibitors.

Author information

1
Molecular and Cellular Biology Research, Sunnybrook and Women's College Health Sciences Centre, S-218, 2075 Bayview Avenue, Toronto, Ontario M4N 3M5, Canada. robert.kerbel@swchsc.on.ca

Abstract

Angiogenesis inhibitors are a new class of drugs, for which the general rules involving conventional chemotherapy might not apply. The successful translation of angiogenesis inhibitors to clinical application depends partly on the transfer of expertise from scientists who are familiar with the biology of angiogenesis to clinicians. What are the most common questions that clinicians ask as they begin to test angiogenesis inhibitors in cancer clinical trials?

PMID:
12360276
DOI:
10.1038/nrc905
[Indexed for MEDLINE]
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