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Med J Aust. 2002 Oct 7;177(7):352-5.

Ross River virus disease in tropical Queensland: evolution of rheumatic manifestations in an inception cohort followed for six months.

Author information

1
Developmental Disability Unit, School of Population Health, University of Queensland, Mater Hospital, Raymond Terrace, South Brisbane, QLD 4101, Australia. D.Harley@sph.uq.edu.au

Abstract

OBJECTIVE:

To describe the natural history of rheumatic manifestations of Ross River virus (RRV) disease.

DESIGN:

Prospective longitudinal clinical review.

SETTING:

North Queensland local government areas of Cairns, Douglas, Mareeba and Atherton during January to May 1998.

PARTICIPANTS:

General practice patients diagnosed with RRV disease on the basis of symptoms and a positive RRV IgM result.

MAIN OUTCOME MEASURES:

Rheumatic symptoms and signs assessed as soon as possible after disease onset and on two subsequent occasions (up to 6.5 months after onset).

RESULTS:

57 patients were recruited, 47 of whom were reviewed three times (at means of 1.1, 2.4 and 3.6 months after disease onset). Results are reported for these 47: 46 (98%) complained of joint pain at first review, with the ankles, wrists, fingers, knees and metacarpophalangeal joints (II-IV) most commonly involved. Prevalence of joint pain decreased progressively on second and third reviews, both overall (92% and 68% of patients, respectively), and in the five joints most commonly affected. The prevalence of other common rheumatic symptoms and signs, and use of non-steroidal anti-inflammatory drugs, also progressively declined over the three reviews.

CONCLUSIONS:

Earlier studies may have overestimated the prevalence and duration of symptoms in RRV disease. Progressive resolution over 3-6 months appears usual.

PMID:
12358576
[Indexed for MEDLINE]

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