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Curr Opin Microbiol. 2002 Oct;5(5):478-82.

Toward rapid real-time molecular diagnostic to guide smart use of antimicrobials.

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Centre de Recherche en Infectiologie de l'Université Laval, Centre Hospitalier Universitaire de Québec (Pavillon CHUL), 2705 Boul. Laurier Sainte-Foy, and Division de Microbiologie, Faculté de Médecine, Université Laval, Québec, Canada G1V 4G2.


Current microbial diagnostic is too slow to provide clinically useful information for the physician to prescribe, only when needed, the appropriate antibiotics. New advances in real-time PCR promise results that will come fast enough to revolutionise the practice of medicine. These novel, fully integrated devices, coupled with appropriate databases, will insure better management of patients, should reduce health costs, and could impact on the spread of antibiotic resistance.

[Indexed for MEDLINE]

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