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Br J Clin Pharmacol. 1975 Feb;2(1):69-72.

Changes in drug metabolism with increasing age: 1. warfarin binding and plasma proteins.

Abstract

1 A decrease was found in the binding capacity of elderly people for warfarin. 2 The decrease in binding correlated with a fall in plasma albumin concentrations. 3 No changes in the association constant were observed.

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