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Nihon Kokyuki Gakkai Zasshi. 2002 Jun;40(6):499-502.

[Minute pulmonary meningothelial-like nodules: a case report].

[Article in Japanese]

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Pulmonary Division, Second Department of Internal Medicine, Saitama Medical School, Saitama.


The presence of multiple small nodular shadows on a routine chest radiograph was noticed in a 56-year-old woman who had undergone a left mastectomy on the diagnosis of breast cancer 8 years before. Chest CT films revealed small nodules scattered beneath the pleura mainly in both lower lobes. A biopsy was performed during video-assisted thoracoscopy to rule out metastasis from breast cancer. Biopsy specimens showed spindle--or oval-shaped cells arranged in nests associated with a dedicated network of capillaries. These findings were compatible with minute meningothelium-like nodules (MN). The pathogenesis of MN is still unknown. It is common in elderly women, and the prognosis is excellent without any treatment. MN is an important disease in the differential diagnosis of multiple nodular shadows found on chest CT.

[Indexed for MEDLINE]

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