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Curr Opin Biotechnol. 2002 Aug;13(4):329-32.

Production of recombinant proteins in fermenter cultures of the yeast Pichia pastoris.

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1
Department of Biological Sciences, University of the Pacific, 3601 Pacific Avenue, Stockton, California 95211, USA.

Abstract

The Pichia pastoris expression system offers economy, ease of manipulation, the ability to perform complex post-translational modifications, and high expression levels. Using this system, recent advances have been made in the quality of recombinant proteins in fermenter culture and in the quality of the protein product, namely improved secretion signals and glycosylation patterns.

PMID:
12323354
[Indexed for MEDLINE]
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