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China Popul Newsl. 1986 Feb;3(1):3-6.

New progress in research on contraceptive technology.



Considerable progress has been made in China's contraceptive research and development during the country's 6th Five Year Plan because of the cooperation among the relevant institutes. The IUD is the most popular contraceptive method in China. Women who choose the IUD account for 40% in all age groups of reproductive women. Consequently, the IUD is 1 of the priorities in research programs. Progress in research on the IUD includes the following: the normal latitude data of uteri in Chinese women has been established, and the data can be used as a reference for the analysis of morphosis of Chinese women at childbearing age for the selection of IUDs; the clinical control research results demonstrates that the continuation rate of TCu-200, which accounts for 99.91%, is higher than the other 2 types of IUD, TCu220 and VCu200; the IUD is effective, safe, and applicable when it is inserted soon after delivery, cesarean section, early induced abortion, curettage of uterine cavity, and on the 3rd or 5th day of menstruation and 30-70 days after delivery; and the hemostatic therapy is effective to some extent after the administration of flufenamic acid, transamic acid, aprotinin, and Xuening tablets (traditional Chinese medicine) for prevention and treatment of hemorrhagic reaction. The priority in basic medicine research is on the mechanism of hemorrhagic reaction of the uterus caused by the IUD. The research in morphology, histology, and biochemistry focuses on the change in the endometrium before and after the insertion of the IUD and the relation between bleeding and change of fibrinokinase activation and prostaglandin. Contraceptive research in the 6th Five Year Plan also covers 3 types of oral contraceptives, 2 types of injections, 2 types of intravaginal devices, 2 types of spermicide, 2 types of medical membrane, gossypol, and an occlusive agent for vas occlusion. Information has been gathered on the change in the endometrium after taking long lasting oral contraceptives. The clinical observation of 60 women of childbearing age who have used spermicide for 4-10 years demonstrates that 2 types of home-made spermicide, which are harmless to the functions of the liver and kidney, fail to affect the menstrual cycle. Certain causes of the irreversibility of spermatogenesis have been found in the research on the testicle biopsy of men who take gossypol. Some achievements have been disseminated for public use, and some research programs are to be continued into the 7th Five Year Plan.

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