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Curr Opin Cell Biol. 2002 Oct;14(5):587-93.

Regulation of endothelial cell contacts during leukocyte extravasation.

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Max-Planck-Institute of Vascular Biology, Institute of Cell Biology, ZMBE University of M√ľnster, Von-Esmarch-Strasse 56, D-48149 Muenster, Germany.


The molecular mechanisms that control the opening and formation of endothelial cell contacts are of central importance for leukocyte extravasation, endothelial permeability and angiogenesis. Progress has been made in identifying novel membrane proteins at endothelial cell contacts as well as novel mechanisms that control interendothelial adhesiveness and transendothelial migration of leukocytes.

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