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Infect Immun. 2002 Oct;70(10):5751-8.

Independent translocation of two micronemal proteins in developing Plasmodium falciparum merozoites.

Author information

1
The Walter and Eliza Hall Institute of Medical Research. School of Botany, University of Melbourne, Melbourne, Australia.

Abstract

Apical membrane antigen 1 of Plasmodium falciparum (PfAMA1) contains an N-terminal propeptide that is removed prior to the translocation of the mature protein onto the merozoite surface. We localized unprocessed PfAMA1 to the microneme organelles of the intraerythrocytic schizont. The results have suggested that the processed form of PfAMA1 translocates from the microneme compartment independently of another microneme protein, EBA175, which is also involved in the invasion of human erythrocytes.

PMID:
12228305
PMCID:
PMC128307
DOI:
10.1128/iai.70.10.5751-5758.2002
[Indexed for MEDLINE]
Free PMC Article

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