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J Pediatr. 2002 Sep;141(3):441-4.

Central precocious puberty in girls with Williams syndrome.

Author information

1
University Hospital Kiel, Christian-Albrechts-Universit├Ąt zu Kiel, Germany.

Abstract

We report an estimated prevalence of precocious puberty of 1 in 5 to 6 girls with Williams syndrome (18.3%). Mean menarcheal age of 86 girls with Williams syndrome was 11.5 +/- 1.7 (+/-SD) years. Distribution of menarcheal age was significantly different from that in normal girls (12.9 +/- 1.1 years; n = 759).

PMID:
12219071
DOI:
10.1067/mpd.2002.127280
[Indexed for MEDLINE]

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