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Bioinformatics. 2002 Sep;18(9):1276-7.

PeCoP: automatic determination of persistently conserved positions in protein families.

Author information

1
Department of Molecular Genetics and Biotechnology, The Hebrew University--Hadassah Medical School, 91120, Jerusalem, Israel. idoerg@burnham.org

Abstract

PeCoP is a WWW-based service which accepts a protein sequence, and reports positions that are conserved in close and distant sequence family members. The collation of family members is performed using iterative PSI-BLAST runs. Examining positional conservation in close and distant family members enables a better selection of positions that may play a role in determining the protein's structure and function.

AVAILABILITY:

http://bioinformatics.org/pecop

CONTACT:

idoerg@burnham.org

SUPPLEMENTARY INFORMATION:

http://bioinformatics.org/pecop/about_pecop

PMID:
12217925
[Indexed for MEDLINE]

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