Format

Send to

Choose Destination
Trends Microbiol. 2002 Sep;10(9):401-5.

Does multiple infection select for raised virulence?

Author information

1
Génétique et Environnement, ISEM, University of Montpellier II, Place Eugene Bataillon, 34095, Montpellier, France. brown@isem.univ-montp2.fr

Abstract

Classical models of virulence evolution conclude that the increased competition favoured by multiple infection will select for increasing consumption and deterioration of the host resource, or 'virulence'. However, recent empirical and theoretical studies suggest that this view of virulence has some shortcomings. Here, we argue that the evolutionary consequences of multiple infection depend critically on whether the exploitation rate of an individual parasite is governed directly by the behaviour of the individual, or whether it is limited by the collective behaviour of the coinfecting group. We illustrate that, depending on the mechanistic details of exploitation, multiple infection can select for reduced virulence.

PMID:
12217504
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center