Format

Send to

Choose Destination
Genes Immun. 2002 Sep;3(6):331-7.

Genetic variability in response to infection: malaria and after.

Author information

1
Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Oxford, UK. david.weatherall@imm.ox.ac.uk

Abstract

Recent studies have shown that the relatively short period of exposure of human populations to malaria has left in its wake a wide range of genetic diversity. And there is growing evidence that other infectious agents have, or are, having the same effect. By integrating further studies of human populations with genetic analyses of susceptibility to murine malaria it should now be possible to determine some of the mechanisms involved in the variation of susceptibility to infectious disease, information which may have important practical implications for both the diagnosis and better management of these conditions.

PMID:
12209359
DOI:
10.1038/sj.gene.6363878
[Indexed for MEDLINE]
Free full text

Supplemental Content

Full text links

Icon for Nature Publishing Group
Loading ...
Support Center