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Nat Rev Cancer. 2002 Sep;2(9):683-93.

Molecular imaging of cancer with positron emission tomography.

Author information

1
Crump Institute for Molecular Imaging, Department of Molecular and Medical Pharmacology, UCLA School of Medicine, 700 Westwood Boulevard, Los Angeles, California 90095-1770, USA. sgambhir@mednet.ucla.edu

Abstract

The imaging of specific molecular targets that are associated with cancer should allow earlier diagnosis and better management of oncology patients. Positron emission tomography (PET) is a highly sensitive non-invasive technology that is ideally suited for pre-clinical and clinical imaging of cancer biology, in contrast to anatomical approaches. By using radiolabelled tracers, which are injected in non-pharmacological doses, three-dimensional images can be reconstructed by a computer to show the concentration and location(s) of the tracer of interest. PET should become increasingly important in cancer imaging in the next decade.

PMID:
12209157
DOI:
10.1038/nrc882
[Indexed for MEDLINE]
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