Format

Send to

Choose Destination
Nat Rev Mol Cell Biol. 2002 Sep;3(9):697-702.

Signalling shortcuts: cell-surface receptors in the nucleus?

Author information

1
Department of Pathology, 713 Scaife, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA. wellsa@msx.upmc.edu

Abstract

Do cell-surface growth-factor receptors and their ligands accumulate in the nucleoplasm under physiological conditions? And, if so, how do they get there and what function do they serve in this location? Recent advances have provided tantalizing hints to the answers to these questions, and hold the key to identifying a new mode of signal transduction.

PMID:
12209129
DOI:
10.1038/nrm905
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Nature Publishing Group
Loading ...
Support Center