Synthesis and evaluation of transition-state analogue inhibitors of alpha-1,3-fucosyltransferase

Angew Chem Int Ed Engl. 2002 Aug 16;41(16):3041-4. doi: 10.1002/1521-3773(20020816)41:16<3041::AID-ANIE3041>3.0.CO;2-V.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Chelating Agents
  • Enzyme Inhibitors / chemical synthesis*
  • Enzyme Inhibitors / pharmacology
  • Fucose / analogs & derivatives*
  • Fucose / chemical synthesis
  • Fucose / pharmacology
  • Fucosyltransferases / antagonists & inhibitors*
  • Structure-Activity Relationship
  • Thiazoles / chemical synthesis
  • Thiazoles / chemistry
  • Thiazoles / pharmacology

Substances

  • Chelating Agents
  • Enzyme Inhibitors
  • Thiazoles
  • Fucose
  • Fucosyltransferases
  • galactoside 3-fucosyltransferase