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Cell. 2002 Aug 23;110(4):403-6.

Competition and compensation: coupled to death in development and cancer.

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1
Department of Cell Biology, University of Texas Southwestern Medical Center, 75390, USA. john.abrams@utsouthwestern.edu

Abstract

Developing systems exhibit robust and tolerant properties in the form of compensation and competition within cell groups. Fundamentally, these behaviors are governed by mechanisms that elicit proliferation and apoptosis. Recent insights from the Drosophila system implicate new determinants that specify "winners" and "losers" in this process.

PMID:
12202030
[Indexed for MEDLINE]
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