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Curr Opin Genet Dev. 2002 Oct;12(5):548-57.

Developmental regulation of somite derivatives: muscle, cartilage and tendon.

Author information

1
Harvard Medical School, Department of Genetics, 200 Longwood Avenue, Boston, Massachusetts 02115, USA.

Abstract

Recent research has broadened significantly our understanding of how the somite, a specialized mesodermal structure found in vertebrate embryos, gives rise to the cartilage, muscle and tendon cell lineages. The specification of somite derivatives involves the action of patterning signals secreted from adjacent tissue combined with the activation, in particular somitic compartments, of genes promoting cell lineage specification.

PMID:
12200160
DOI:
10.1016/s0959-437x(02)00339-8
[Indexed for MEDLINE]

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