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Dev Cell. 2002 Aug;3(2):150-2.

REV-ving up the clock.

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1
Department of Pathology and Laboratory Medicine, Philadelphia, PA 19104, USA.

Abstract

Circadian rhythms are generated by a transcription/translation feedback loop consisting of two limbs, one positive and one negative. The nuclear orphan receptor, REV-ERBalpha, is identified as a molecular link coupling these two limbs.

PMID:
12194843
[Indexed for MEDLINE]
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