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Mol Cell. 2002 Aug;10(2):215-6.

An ESCRT into the endosome.

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1
Centre for Molecular Medicine and Therapeutics, Department of Medical Genetics, University of British Columbia, Vancouver, British Columbia, Canada.

Abstract

Multivesicular endosomes sort ubiquitinated membrane proteins for degradation by incorporating them into inwardly budding vesicles. The recent identification of two new oligomeric components of the sorting machinery gives us a detailed view of the complex protein-protein interactions driving this process.

PMID:
12191463
[Indexed for MEDLINE]
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