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Redox Rep. 2002;7(3):137-43.

Antioxidant properties of a Tinospora cordifolia polysaccharide against iron-mediated lipid damage and gamma-ray induced protein damage.

Author information

1
Bio-Organic Division, Bhabha Atomic Research Centre, Mumbai 400 085, India.

Abstract

The antioxidant activity of an arabinogalactan polysaccharide (TSP) isolated from Tinospora cordifolia, an Indian medicinal plant, was studied. The polysaccharide showed good protection against iron-mediated lipid peroxidation of rat brain homogenate as revealed by the thiobarbituric acid reactive substances (TBARS) and lipid hydroperoxide (LOOH) assays. TSP also provided significant protection to protein against gamma-ray induced damage. The protective action can possibly be explained by its very high reactivity towards DPPH, superoxide radicals and the most damaging of radicals, the hydroxyl radical.

PMID:
12189043
DOI:
10.1179/135100002125000370
[Indexed for MEDLINE]

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