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Semin Oncol Nurs. 2002 Aug;18(3 Suppl 3):6-11.

Pathophysiology, signs, and symptoms of acute tumor lysis syndrome.

Author information

1
Nell Hodgson Woodruff School of Nursing, Emory University, 1520 Clifton Rd, Atlanta, GA 30322-4207, USA.

Abstract

OBJECTIVES:

To provide a review of the pathophysiology and corresponding signs and symptoms of tumor lysis syndrome (TLS); to review clinical and laboratory monitoring parameters.

DATA SOURCES:

Primary and tertiary literature and clinical experience.

CONCLUSIONS:

An understanding of the pathophysiology of TLS, meticulous assessment for signs and symptoms and monitoring of laboratory data, as well as early recognition of problems are essential for optimal patient outcomes.

IMPLICATIONS FOR NURSING PRACTICE:

Knowledge of the pathophysiology of TLS will assist the oncology nurse in better understanding the overall syndrome and allow improved patient care management through close clinical and laboratory monitoring of signs and symptoms, and, ideally, promote a proactive approach to managing TLS.

PMID:
12184050
[Indexed for MEDLINE]
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