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Lett Appl Microbiol. 2002;35(3):181-4.

Helichrysum italicum extract interferes with the production of enterotoxins by Staphylococcus aureus.

Author information

1
Dipartimento Farmaco-Biologico, Sezione Microbiologia, Facoltà di Farmacia, Università di Messina, Villaggio Annunziata, Italy. atnostro@pharma.unime.it

Abstract

AIMS:

The purpose of this work was to evaluate the effect of Helichrysum italicum extract on enterotoxin (A-D) production by Staphylococcus aureus strains.

METHODS AND RESULTS:

The production of enterotoxins A-D in the presence or absence of H.italicum diethyl ether extract was estimated in microtiter plates using a reversed passive latex agglutination (SET-RPLA) kit (Oxoid, Basingstoke, UK). The results indicate that, in culture medium, inhibition of staphylococcal growth and enterotoxins appeared with 250-125 microg ml(-1) of the extract. Lower concentrations of the extract (62.5-31.25 microg ml(-1)) did not affect the final viable count of Staph. aureus but reduced the production of enterotoxins B and C.

CONCLUSIONS:

H. italicum interferes with growth and production of enterotoxins by Staph. aureus.

SIGNIFICANCE AND IMPACT OF THE STUDY:

There is considerable interest in the use of natural compounds as alternative methods to control undesirable pathogenic micro-organisms.

PMID:
12180937
[Indexed for MEDLINE]
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