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Biochim Biophys Acta. 2002 Aug 8;1583(3):311-4.

Influence of the APOC3 -2854T>G polymorphism on plasma lipid levels: effect of age and gender.

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1
The Hugh Sinclair Unit of Human Nutrition, School of Food Biosciences, The University of Reading, Whiteknights, UK. a.m.minihane@reading.ac.uk

Abstract

The APOC3 -2854T>G polymorphism lies in the APOC3-A4 intergenic region. In a group of healthy adults, this polymorphism was associated with circulating triglycerides, with 55% lower fasting levels in the homozygous wild-type (TT) compared to the homozygous rare allele (GG) genotype. Age and gender had a significant impact on genotype-triglyceride interactions.

PMID:
12176399
[Indexed for MEDLINE]
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