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Trends Biotechnol. 2002 Sep;20(9):361-4.

Proteomics goes quantitative: measuring protein abundance.

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Department Cell Biology, Harvard Medical School, Boston, MA 02115, USA.


Protein-based methodologies are catching up with established DNA-based methods at an astonishing speed. Recent developments in mass spectrometry enable high-throughput automated identification of proteins as is already the case with DNA sequencing methods. Furthermore, methods for the quantitation of relative protein abundance at the protein level are getting more advanced, which should complement gene expression monitoring at the mRNA level.

[Indexed for MEDLINE]

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