Send to

Choose Destination
Neuron. 2002 Aug 1;35(3):412-4.

Helping thy neighbors: spillover at the mossy fiber glomerulus.

Author information

Department of Neurobiology, School of Medicine, University of California-Los Angeles, Los Angeles, CA 90095, USA.


Neurotransmitter "spillover" between neighboring synapses challenges the principle of synapse specificity. In this issue of Neuron, show that release from neighboring presynaptic sites contributes significantly to AMPA receptor-mediated postsynaptic currents at cerebellar mossy fiber synapses. Unexpectedly, spillover is predicted to improve the reliability and reduce the variability of transmission at this glomerular synapse.

[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center