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Arch Otolaryngol Head Neck Surg. 2002 Aug;128(8):909-12.

Partial laryngectomy to treat early glottic cancer after failure of radiation therapy.

Author information

1
Department of Otolaryngology-Head and Neck Surgery, Graduate School of Medicine, University of Tokyo, Japan. makiko@jd5.so-net.ne.jp

Abstract

OBJECTIVE:

To evaluate the role of partial laryngectomy to treat glottic cancer after failure of radiation therapy.

DESIGN:

A 12-year retrospective outcome analysis.

SETTING:

University referral center.

PATIENTS:

A total of 19 patients who underwent partial laryngectomy to treat glottic cancer after failure of radiation therapy.

RESULTS:

The follow-up period in this group ranged from 31 to 144 months. After surgery, a laryngocutaneous fistula was observed in 4 cases, and flap necrosis occurred in 2, but these complications were successfully managed. Maximum phonation time after surgery ranged from 3 to 28 seconds (median phonation time, 10.2 seconds). Of these 19 patients, 3 developed local recurrence. These cases were successfully treated with total laryngectomy. A surgical margin of less than 1 mm was found to be a significant risk factor for local recurrence after partial laryngectomy.

CONCLUSIONS:

These results indicate that partial laryngectomy is a useful option for the treatment of irradiation failure in the treatment of stage I and stage II vocal cord carcinomas. However, careful follow-up is mandatory for patients with a small surgical margin.

PMID:
12162769
[Indexed for MEDLINE]
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