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Microbiol Immunol. 2002;46(6):359-63.

Hemagglutinating factor (HAF) associated with adhesiveness in enteroinvasive Escherichia coli (EIEC).

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Departamento de Microbiologia e Imunologia, Universidade Estadual de Campinas (Unicamp), SP, Brazil.


A cell-associated mannose-resistant hemagglutinating factor (HAF) was extracted from enteroinvasive Escherichia coli (EIEC) serotype O124:H- by sonication. Ultrastructural analysis of EIEC and immunocytochemical assays with the cell-free HAF and EIEC bacterial cells on HeLa cells, suggested that the HAF is a non-fimbrial putative adhesive factor that mediates in vivo adherence of EIEC to human epithelial cells.

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