Rapid development of cortical auditory evoked potentials after early cochlear implantation

Neuroreport. 2002 Jul 19;13(10):1365-8. doi: 10.1097/00001756-200207190-00030.

Abstract

The aim of our research was to estimate the time course of development and plasticity of the human central auditory pathways following cochlear implantation. We recorded cortical auditory-evoked potentials in 3-year-old congenitally deaf children after they were fitted with cochlear implants. Immediately after implantation cortical response latencies resembled those of normal-hearing newborns. Over the next few months, the cortical evoked responses showed rapid changes in morphology and latency that resulted in age-appropriate latencies by 8 months after implantation. Overall, the development of cortical response latencies for the implanted children was more rapid than for their normal-hearing age-matched peers. Our results demonstrate a high degree of central auditory system plasticity during early human development.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Analysis of Variance
  • Auditory Cortex / growth & development
  • Auditory Cortex / physiology*
  • Child, Preschool
  • Cochlear Implants*
  • Deafness / physiopathology
  • Deafness / surgery
  • Evoked Potentials, Auditory / physiology*
  • Humans
  • Infant
  • Neuronal Plasticity / physiology*
  • Reaction Time / physiology