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Cell. 2002 Jul 26;110(2):139-42.

Exploring the neighborhood: adhesion-coupled cell mechanosensors.

Author information

1
Department of Molecular Cell Biology, The Weizmann Institute of Science, 76100, Rehovot, Israel. benny.geiger@weizmann.ac.il

Abstract

Here we discuss recent studies addressing adhesion-coupled mechanosensory processes and consider their molecular nature. Are cells using stretch-activated ion channels to explore the extracellular environment surrounding them, or do they use for that purpose the submembrane protein network that interconnects integrin receptors with the actin cytoskeleton?

PMID:
12150922
[Indexed for MEDLINE]

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