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Chem Biol. 2002 Jul;9(7):777-9.

Sno-capped: 5' ends of preribosomal RNAs are decorated with a U3 SnoRNP.

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  • 1Department of Biochemistry, Biophysics and Molecular Biology, Iowa State University, Ames, IA 50011, USA.


Efficient ribosome biosynthesis is crucial for cell viability. Work recently published in Nature demonstrates that a large ribonucleoprotein processes 18S rRNA in S. cerevisiae, indicating that macromolecular particles regulate ribosome maturation and revealing the complex nature of this process.

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