Format

Send to

Choose Destination
Int J Dev Biol. 2002;46(4):535-44.

PAX genes in development and disease: the role of PAX2 in urogenital tract development.

Author information

1
Department of Pathology, University of Otago, Dunedin, New Zealand. meccles@otago.ac.nz

Abstract

PAX genes play an important role in fetal development. Moreover, heterozygous mutations in several PAX genes cause human disease. Here we review the role of PAX2 in kidney development, focusing on the morphological effects of PAX2 mutations. We discuss the role of PAX2 in the context of an inhibitory field model of kidney branching morphogenesis and summarize recent progress in this area.

PMID:
12141441
[Indexed for MEDLINE]
Free full text

Supplemental Content

Full text links

Icon for The International Journal of Developmental Biology
Loading ...
Support Center