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Curr Opin Neurobiol. 2002 Aug;12(4):366-71.

Receptors for bitter and sweet taste.

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  • 1Centre Européen des Sciences du Goût, Centre National de la Recherche Scientifique, 15 Rue Hugues Picardet, 21000, Dijon, France.


The identification of two families of receptors, T1Rs and T2Rs, for sweet and bitter taste stimuli has opened the door to understanding some of the basic mechanisms underlying taste transduction in mammals. Studies of the functions of these receptors and their patterns of expression provide important information regarding the detection of structurally diverse taste compounds and the manner in which different taste qualities are encoded in the mouth.

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