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Crit Care. 2002 Jun;6(3):190-1. Epub 2002 May 9.

Cortisol replacement for severe sepsis and septic shock: what should I do?

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  • 1Intensive Care Department, Raymond PoincarĂ© University Hospital, Garches, France. djillali.annane@rpc.ap-hop-paris.fr

Abstract

Based on several recently completed randomized controlled trials, cortisol replacement is likely to become a standard of care for vasopressor dependent septic shock. Further studies are needed in order to accomplish whether this treatment should be limited to patients with a blunted cortisol response to corticotrophin. Similarly, in patients with severe sepsis who do not need vasopressors, the benefit/risk ratio of cortisol replacement remains to be assessed.

PMID:
12133175
PMCID:
PMC137442
[PubMed - indexed for MEDLINE]
Free PMC Article
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