Format

Send to

Choose Destination
See comment in PubMed Commons below
Antimicrob Agents Chemother. 2002 Aug;46(8):2668-70.

Chemiosmotic mechanism of antimicrobial activity of Ag(+) in Vibrio cholerae.

Author information

1
Department of Microbiology, University of Manitoba, Winnipeg, Manitoba R3T 2N2, Canada.

Abstract

Although the antimicrobial effects of silver salts were noticed long ago, the molecular mechanism of the bactericidal action of Ag(+) in low concentrations has not been elucidated. Here, we show that low concentrations of Ag(+) induce a massive proton leakage through the Vibrio cholerae membrane, which results in complete deenergization and, with a high degree of probability, cell death.

PMID:
12121953
PMCID:
PMC127333
[Indexed for MEDLINE]
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for PubMed Central
    Loading ...
    Support Center