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Chem Commun (Camb). 2002 Feb 7;(3):226-7.

Polyclonal antibody-catalysed hydrolysis of a beta-lactam.

Author information

1
School of Pharmacy and Biomolecular Sciences, University of Brighton, Cockcroft Building, Moulsecoomb, Brighton, UK BN2 4GJ.

Abstract

We report the first example of antibody-catalysed hydrolysis of a beta-lactam where the antibodies were generated by a simple transition-state analogue; in this example the antibodies are polyclonal.

PMID:
12120377
DOI:
10.1039/b110135h
[Indexed for MEDLINE]

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