A randomised controlled trial of the closure or non-closure of peritoneum at caesarean section: effect on post-operative pain

BJOG. 2002 Jun;109(6):694-8. doi: 10.1111/j.1471-0528.2002.00153.x.

Abstract

Objective: To compare the analgesic requirement in the post-operative period after closure or non-closure of the peritoneum at the caesarean delivery with a standardised anaesthetic and surgical technique.

Design: A randomised double-blind controlled trial was performed on 100 women who underwent elective caesarean delivery.

Main outcome measures: Analgesic requirement assessed by morphine usage via patient controlled analgesia pump over the first 24-hour period after surgery, oral analgesia used during the first four days, postoperative pain assessed by a visual analogue scale and a verbal rating scale, and patient satisfaction assessed by verbal rating scale were the main outcome measures.

Results: Pain scores at 24 hours were similar in both groups (43.5 in closure and 40.5 in non-closure) but during the first 24 hours the non-closure group had used significantly less morphine than the closure group (0.64 mg/kg of body weight vs 0.82 mg/kg, P = 0.04). The patients in non-closure group had significantly higher satisfaction scores after 24 hours than the closure group.

Conclusion: Non-closure of both visceral and parietal peritoneum at the caesarean section produces a significant reduction in the post-operative use of patient controlled analgesia pump morphine and significantly higher patient satisfaction at 24 hours post-operatively.

Publication types

  • Clinical Trial
  • Comparative Study
  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Analgesia, Obstetrical / methods
  • Analgesia, Patient-Controlled / instrumentation
  • Analgesics, Opioid / administration & dosage
  • Cesarean Section / methods*
  • Double-Blind Method
  • Drug Administration Routes
  • Elective Surgical Procedures / methods
  • Female
  • Humans
  • Length of Stay
  • Morphine / administration & dosage
  • Pain Measurement
  • Pain, Postoperative / etiology*
  • Pain, Postoperative / prevention & control
  • Patient Satisfaction
  • Peritoneum / surgery*
  • Pregnancy

Substances

  • Analgesics, Opioid
  • Morphine