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Radiol Clin North Am. 2002 May;40(3):467-82.

New modalities in breast imaging: digital mammography, positron emission tomography, and sestamibi scintimammography.

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Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.


Digital mammography, PET, and sestamibi scintimammography are three new modalities in breast imaging. DM has advantages over film-screen mammography in image storage, retrieval, and processing and may lower the recall rate. Computer-aided detection may increase the sensitivity of mammographic screening without a substantial reduction in specificity. Whereas PET and sestambi scintimammography are not useful in breast cancer screening, PET may play a role in detecting nodal metastases and monitoring treatment response, and sestamibi scintimammography in selected cases may serve as an adjunct to conventional imaging. The cost-effectiveness of these new modalities remains to be evaluated, but all have the potential to significantly advance the diagnosis and management of women with breast cancer.

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