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Biotechnol Bioeng. 2002 Aug 20;79(4):465-71.

Polymer surfaces derivatized with poly(vinyl-N-hexylpyridinium) kill airborne and waterborne bacteria.

Author information

1
Department of Chemistry, Massachusetts Institute of Technology, Cambridge 02139, USA.

Abstract

A facile methodology has been developed for covalently derivatizing the surfaces of common materials with a designed antibacterial polycation, poly(vinyl-N-pyridinium bromide), wherein the first, key step involves surface coating with a nanolayer of silica. Various commercial synthetic polymers derivatized in this manner become bactericidal-they kill up to 99% of deposited, from either an aerosol or an aqueous suspension, Gram-positive and Gram-negative bacteria on contact.

PMID:
12115410
DOI:
10.1002/bit.10299
[Indexed for MEDLINE]

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