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Expert Rev Anticancer Ther. 2001 Dec;1(4):546-54.

New agents for the treatment of renal cell carcinoma.

Author information

1
Division of Hematology/Oncology, Greenebaum Cancer Center, University of Maryland, 22 South Greene Street, Baltimore, MD 21201, USA.

Abstract

One-third of patients with renal cell carcinoma present with unresectable or metastatic disease. Immunotherapy, the current standard treatment, induces response in only 10-20% of patients. Chemotherapy with current agents is minimally effective. Other approaches including allogeneic stem cell transplant, vaccine and gene therapy and signal transduction inhibitors, offer promise in early Phase studies. This paper reviews the current treatment options and promising new agents in development.

PMID:
12113087
DOI:
10.1586/14737140.1.4.546
[Indexed for MEDLINE]

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