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Ann Neurol. 2002 Jun;51(6):786-9.

High headache prevalence among women with hemochromatosis: the Nord-Tr√łndelag health study.

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1
Department of Clinical Neuroscience, Section of Neurology, Norwegian University of Science and Technology, 7006 Trondheim, Norway. knut.hagen@medisin.ntnu.no

Abstract

In this large cross-sectional population-based study, 51,272 persons responded to a headache questionnaire and were screened for hemochromatosis. Phenotypic hemochromatosis and the C282Y/C282Y genotype were both associated with an 80% increase in headache prevalence evident only among women. The reason for this association is unclear, but one may speculate that iron overload alters the threshold for triggering a headache by disturbing neuronal function.

PMID:
12112089
DOI:
10.1002/ana.10209
[Indexed for MEDLINE]
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