Format

Send to

Choose Destination
Neurol Sci. 2002 Apr;23(1):41-3.

Donepezil in the treatment of hallucinations and delusions in Parkinson's disease.

Author information

1
Department of Neurological Sciences, La Sapienza University, Viale del'Università 30, I-00185 Rome, Italy.

Abstract

As cholinergic mechanisms may be at least partially responsible for hallucinations and delusions in Parkinson's disease (PD), we conducted an open study in 8 PD patients to assess the efficacy and tolerability of the cholinesterase inhibitor donepezil, 5 mg at bedtime for two months, in the treatment of these complications. Hallucinations and delusions improved significantly in all patients. Donezepil was overall well tolerated, but a deterioration in motor disability was noted in 2 out of 8 patients.

PMID:
12111620
DOI:
10.1007/s100720200022
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Springer
Loading ...
Support Center