Format

Send to

Choose Destination
Cell. 2002 Jun 28;109(7):793-6.

Destabilizing influences in apoptosis: sowing the seeds of IAP destruction.

Author information

1
Molecular Cell Biology Laboratory, Department of Genetics, Trinity College, Dublin 2, Ireland. martinsj@tcd.ie

Abstract

Inhibitor of apoptosis proteins (IAPs) can block apoptosis through interactions with members of the caspase family of cysteine proteases. Recent developments suggest that ubiquitin-proteasome mediated destruction of the Drosophila IAP, DIAP1, is a key event during the initiation of programmed cell death in the fly.

PMID:
12110175
DOI:
10.1016/s0092-8674(02)00802-4
[Indexed for MEDLINE]
Free full text

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center