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Psychopharmacology (Berl). 2002 Jun;162(1):11-7. Epub 2002 Apr 17.

The effects of second-generation antipsychotics on cognitive functioning and psychosocial outcome in schizophrenia.

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1
Department of Biological Psychiatry, Innsbruck University Clinics, Anichstrasse 35, 6020 Innsbruck University Clinics, Anichtrasse 35, 6020 Innsbruck, Austria. elisabeth.weiss@uibk.ac.at

Abstract

Neuropsychological deficits seem to be a major predictor of psychosocial outcome in patients with schizophrenia. Second-generation antipsychotics have shown greater promise in treating neuropsychological deficits than conventional antipsychotic drugs. This article summarizes the effect of newer antipsychotics on cognitive functioning and the implications for functional outcome. In this context it also addresses several methodological and conceptional issues that limited the comparison of these studies.

PMID:
12107611
DOI:
10.1007/s00213-002-1053-y
[Indexed for MEDLINE]
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