Format

Send to

Choose Destination
Microbes Infect. 2002 Jul;4(9):887-95.

Genetic approaches to the study of Toll-like receptor function.

Author information

1
Department of Host Defense, Research Institute for Microbial Diseases, Osaka University, 3-1 Yamada-oka, Suita, Osaka, Japan.

Abstract

The Toll-like receptor (TLR) family plays a role in sensing invading pathogens. Ten members have been reported to date, seven of which were found to recognize discrete bacterial components. Mouse models lacking each TLR and its signaling molecule are useful tools for the analysis of the innate immune system.

PMID:
12106781
DOI:
10.1016/s1286-4579(02)01615-5
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center