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Curr Opin Genet Dev. 2002 Aug;12(4):452-8.

Early induction of neural crest cells: lessons learned from frog, fish and chick.

Author information

1
Millennium Nucleus in Developmental Biology, Facultad de Ciencias, Universidad de Chile, Las Palmeras 3425, Casilla 653, Santiago, Chile. maybar@uchile.cl

Abstract

The identification of genes in Xenopus, chick and zebrafish expressed early in prospective neural crest (NC) cells has challenged the previous view that the NC is induced during the closure of the neural tube. We compare here the early inductive molecular mechanisms in different organisms and, despite observed differences, propose a general common model for NC induction.

PMID:
12100892
DOI:
10.1016/s0959-437x(02)00325-8
[Indexed for MEDLINE]

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