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J Virol. 2002 Aug;76(15):7855-9.

Handedness of the herpes simplex virus capsid and procapsid.

Author information

1
Laboratory of Structural Biology, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA.

Abstract

The capsid of herpes simplex virus has an icosahedral surface lattice with a nonskew triangulation number, T=16. Nevertheless, the proteins arrayed on this lattice necessarily have an intrinsic handedness. We have determined the handedness of both the herpes simplex virus type 1 capsid and its precursor procapsid by a cryoelectron microscopic tilting method.

PMID:
12097597
PMCID:
PMC136369
DOI:
10.1128/jvi.76.15.7855-7859.2002
[Indexed for MEDLINE]
Free PMC Article

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