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J Vasc Surg. 2002 Jul;36(1):194-5.

A brief note on overlapping confidence intervals.

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Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada.


Clinical researchers frequently assess the statistical significance of the difference between two means by examining whether the two 95% confidence intervals overlap. The purpose of this brief communication is to illustrate that the 95% confidence intervals for two means can overlap and yet the two means can be statistically significantly different from one another at the alpha = 0.05 level.

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