Format

Send to

Choose Destination
Curr Opin Immunol. 2002 Aug;14(4):471-7.

Interactions between dead cells and dendritic cells in the induction of antiviral CTL responses.

Author information

1
Laboratory of Molecular Neuro-Oncology, The Rockefeller University New York, New York, NY 10021, USA.

Abstract

Dendritic cells - professional antigen-presenting cells - are key players for activating adaptive immune responses against viruses. Apoptosis or lytic cell death often accompanies viral infection. Dendritic cells can acquire infected dead or dying cells as exogenous sources of antigens for presentation on MHC class I and II molecules to initiate T cell responses. This pathway of activating T cells may be critical for the development of effective antiviral immunity in vivo.

PMID:
12088682
DOI:
10.1016/s0952-7915(02)00358-8
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center